Post Doctoral Rsrch Assoc

SUMMARY

Under the general supervision of the Principal Investigator, and within established policies and procedures, the Post-Doctoral Research Associate conducts laboratory-based brain tumor research within the Department of Neurosurgery at Brown University Health. This position integrates advanced experimental and computational approaches, including multi-omics and epigenetic data analysis, and quantitative analysis of human and patient-derived cells, tissues, and imaging datasets. The role also involves evaluating responses to therapeutic interventions such as drug and radiation treatments.

Key responsibilities include:

• Conducting statistical and transcriptomic analyses
• Developing stochastic and mechanistic simulation models
• Performing computational image analysis
• Applying machine learning approaches to biomedical data

The Post-Doctoral Research Associate will prepare scientific figures, technical reports, and manuscripts for publication and presentation, and will contribute to grant applications and funded research initiatives. This position is critical to advancing the laboratory’s scientific mission and sustaining competitive research programs.

Brown University Health employees are expected to successfully role model the organization's values of Compassion, Accountability, Respect, and Excellence as these values guide our everyday actions with patients, customers, and one another. In addition to our values, all employees are expected to demonstrate the core Success Factors which tell us how we work together and how we get things done. The core Success Factors include:

• Instill Trust and Value Differences
• Patient and Community Focus and Collaborate

RESPONSIBILITIES

• Conduct laboratory research using human and patient-derived cell cultures to support neuroscience and brain tumor studies.
• Design and execute cell-based assays—such as live-cell microscopy, proliferation assays, and migration assays—to generate robust quantitative research data.
• Perform molecular analyses, including immunostaining, Western blotting, and RNA sequencing workflows.

Computational and Data Analysis

• Apply statistical, computational, and bioinformatic methods to analyze experimental and clinical datasets, including gene expression and treatment response data.
• Perform computational imaging analysis of tumor and cellular behavior.

Research Development and Support

• Assist Principal Investigator in the design and implementation of experimental and computational protocols aligned with funded research objectives.
• Manage laboratory reagents, biomaterials, and experimental substrates to ensure research readiness and continuity.
• Contribute to the preparation of technical documentation, presentation, publication, and grant application. If desired, the Post-Doctoral Research Associate may have an opportunity to pursue grants as Principal Investigator.
• Participate in departmental meetings and collaborative research initiatives within Neurosurgery and affiliated academic programs.
• Contribute to project coordination and management, including tracking milestones, timelines, and deliverables across studies.
• Perform other duties as assigned.

MINIMUM QUALIFICATIONS

BASIC KNOWLEDGE

Minimum qualifications include a Ph.D. degree in:

• Biology
• Biophysics
• Biomedical Engineering
• Bioinformatics
• Statistics
• Or a related field

No specific licensure or certification is required.

EXPERIENCE

Candidates must have a minimum of five years of relevant research experience in a biomedical or related laboratory environment. This experience may include undergraduate or graduate research training. Required experience includes:

• Mammalian cell culture techniques
• Molecular biology or imaging assays
• Bioinformatic and statistical data analysis

Candidates must demonstrate:

• Ability to design and execute experimental and computational protocols independently
• Strong research documentation and organizational skills
• Effective written and verbal communication skills in English
• Basic programming, computational, or statistical skills
• Ability to work collaboratively in a multidisciplinary research environment

PREFERRED QUALIFICATIONS

• Strong background in brain oncology research and drug discovery
• Experience in project management, including planning, prioritization, and coordination of multicomponent research projects
• Proven track record in grant writing or application development, including fellowships or multi-investigator proposals
• Demonstrated experience in high-throughput screening platforms
• Prior experience in collaboration with pharmaceutical industry or biotechnology company

SUPERVISORY RESPONSIBILITY

This position does not include formal supervisory responsibilities. The Post-Doctoral Research Associate works under the direction of the Principal Investigator and may provide informal training and guidance to students, trainees, or new laboratory members as needed.

Pay Range

$58,489.60 - $96,491.20

Location

Rhode Island Hospital - 593 Eddy Street Providence, Rhode Island 02903

Work Type

8:00 am - 5:00 pm

Work Shift

Day

Daily Hours

8 hours

Driving Required

No

Brown University Health is committed to providing equal employment opportunities and maintaining a work environment free from all forms of unlawful discrimination and harassment.